A virus that cause respiratory illnesses and stomach upsets in children could help in the fight against primary liver cancer, according to a study. Reovirus stimulates the body’s own immune system to kill off the cancerous cells and is also able to kill off the hepatitis C virus – a common cause of primary liver cancer – at the same time, the researchers at the University of Leeds discovered.
These early stage findings are important because primary liver cancer is the third highest cause of cancer deaths worldwide and, if surgery is not an option, the prognosis is poor. Study co-leader Dr Stephen Griffin, Associate Professor of Viral Oncology at the University of Leeds, said: “Ultimately we hope that by simultaneously treating the tumor, and the hepatitis virus that is driving the growth of the tumor, we may provide a more effective therapy and improve the outcomes for patients.
“Current treatments for liver cancer that can’t be removed by surgery are mainly palliative with chemotherapy only tending to prolong life, rather than cure and it can have significant side effects.” The University of Leeds team found that Reovirus was successful in treating both liver cancer cells grown in the laboratory and those taken directly from patients undergoing surgery.
When introduced into the body, Reovirus stimulates an immune system factor known as interferon, which in turn causes the activation of a specific white blood cell called a Natural Killer cell. These Natural Killer cells then kill both the tumor, and cells infected with the hepatitis C virus.
Stimulating the immune system to kill cancer cells is known as immunotherapy. It differs from chemotherapy, in which the actual drugs kill the cancer cells. The researchers are now hoping to start the first in-human clinical trials. Study co-leader Professor Alan Melcher, now Professor of Translational Immunotherapy at the Institute of Cancer Research, London, said: “Our study establishes a completely new type of viral immunotherapy for the most common primary liver cancer type, hepatocellular carcinoma, which has a very poor prognosis in its advanced form.
There is noticeably a bundle to know about this. I assume you made certain nice points in features also.
Thanks for the sensible critique. Me & my neighbor were just preparing to do some research about this. We got a grab a book from our local library but I think I learned more from this post. I’m very glad to see such wonderful information being shared freely out there.
Thanx for the effort, keep up the good work Great work, I am going to start a small Blog Engine course work using your site I hope you enjoy blogging with the popular BlogEngine.net.Thethoughts you express are really awesome. Hope you will right some more posts.
You actually make it seem so easy with your presentation but I in finding this topic to be actually one thing which I feel I’d by no means understand. It kind of feels too complicated and very huge for me. I am looking forward in your subsequent publish, I will try to get the dangle of it!
I’m curious to find out what blog platform you have been utilizing? I’m having some minor security problems with my latest website and I’d like to find something more secure. Do you have any suggestions?
I have not checked in here for a while since I thought it was getting boring, but the last several posts are great quality so I guess I?¦ll add you back to my daily bloglist. You deserve it my friend :)
Wow, amazing blog structure! How long have you ever been blogging for? you made running a blog glance easy. The total glance of your website is great, let alone the content material!
It is perfect time to make a few plans for the longer term and it’s time to be happy. I’ve learn this submit and if I may just I wish to counsel you some interesting things or tips. Maybe you could write subsequent articles referring to this article. I want to read more issues about it!
I always was concerned in this subject and still am, thankyou for putting up.
Good day! Would you mind if I share your blog with my zynga group? There’s a lot of people that I think would really enjoy your content. Please let me know. Cheers
Glad to be one of several visitants on this awesome site : D.
Im now not sure where you are getting your info, however good topic. I must spend some time studying much more or working out more. Thanks for wonderful information I was on the lookout for this information for my mission.
You are my breathing in, I own few blogs and very sporadically run out from to post .
Some truly superb info , Gladiola I noticed this.
I am impressed with this site, rattling I am a big fan .
Fantastic web site. A lot of helpful info here. I’m sending it to a few buddies ans additionally sharing in delicious. And certainly, thank you to your effort!
I’ve read some just right stuff here. Certainly price bookmarking for revisiting. I wonder how a lot effort you put to make this type of great informative web site.
Woah! I’m really loving the template/theme of this website. It’s simple, yet effective. A lot of times it’s tough to get that “perfect balance” between superb usability and visual appeal. I must say that you’ve done a excellent job with this. Also, the blog loads extremely fast for me on Opera. Exceptional Blog!
Some really wonderful information, Gladiolus I detected this. “No men can be lords of our faith, though they may be helpers of our joy.” by John Owen.
I have not checked in here for some time as I thought it was getting boring, but the last few posts are good quality so I guess I?¦ll add you back to my daily bloglist. You deserve it my friend :)
Thanks for the auspicious writeup. It in reality was once a leisure account it. Look complicated to far brought agreeable from you! By the way, how could we keep in touch?
I am often to blogging and i really appreciate your content. The article has really peaks my interest. I am going to bookmark your site and keep checking for new information.
Valuable information. Lucky me I found your website by accident, and I’m shocked why this accident didn’t happened earlier! I bookmarked it.
I’m typically to running a blog and i actually recognize your content. The article has actually peaks my interest. I am going to bookmark your website and maintain checking for new information.
I’d have to examine with you here. Which is not one thing I usually do! I take pleasure in reading a post that may make folks think. Additionally, thanks for permitting me to comment!
Good – I should certainly pronounce, impressed with your web site. I had no trouble navigating through all tabs and related info ended up being truly simple to do to access. I recently found what I hoped for before you know it in the least. Reasonably unusual. Is likely to appreciate it for those who add forums or something, website theme . a tones way for your client to communicate. Excellent task..
An interesting discussion is worth comment. I think that you should write more on this topic, it might not be a taboo subject but generally people are not enough to speak on such topics. To the next. Cheers
I’d have to examine with you here. Which is not one thing I usually do! I take pleasure in reading a post that may make folks think. Additionally, thanks for permitting me to comment!
I like the helpful info you provide in your articles. I’ll bookmark your weblog and check again here frequently. I am quite certain I’ll learn plenty of new stuff right here! Good luck for the next!
I have been browsing online more than 3 hours these days, yet I never discovered any fascinating article like yours. It’s beautiful price sufficient for me. In my view, if all site owners and bloggers made good content as you probably did, the net will be much more helpful than ever before. “It’s all right to have butterflies in your stomach. Just get them to fly in formation.” by Dr. Rob Gilbert.
Hmm is anyone else experiencing problems with the pictures on this blog loading? I’m trying to figure out if its a problem on my end or if it’s the blog. Any feedback would be greatly appreciated.
F*ckin¦ amazing things here. I¦m very happy to peer your article. Thank you so much and i am taking a look ahead to contact you. Will you kindly drop me a e-mail?
Wow! This could be one particular of the most helpful blogs We’ve ever arrive across on this subject. Basically Fantastic. I’m also a specialist in this topic so I can understand your effort.
Hello! I could have sworn I’ve been to this blog before but after browsing through some of the post I realized it’s new to me. Anyways, I’m definitely happy I found it and I’ll be book-marking and checking back frequently!
you are really a good webmaster. The site loading speed is incredible. It seems that you are doing any unique trick. In addition, The contents are masterpiece. you have done a great job on this topic!